Masoumeh Dowlatshahi

Shokoufeh Dowlatshahi[email protected]

Current position
 –    PhD Student in Analytical Chemistry
Chalmers University of Technology, Göteborg, Sweden
Under Supervision of Andrew Ewing and Per Malmberg

Education
–    Master of Science in Chemistry and Bioscience
Chalmers University of Technology, Göteborg, Sweden
–    Master of Science in Analytical Chemistry
Khaje Nasir, Toosi University of Technology, Tehran, Iran

Research

My research is mainly focused on the development and application of two promising label-free imaging techniques, Matrix Assisted Laser Desorption Ionization (MALDI) and Secondary Ion Mass Spectrometry (SIMS) to image, map and detect neuropeptides, lipids and metal ions specifically zinc species in the brain. This is of interest for investigating the underlying chemical mechanisms and changes in biomolecules during the progression of neurological disorders. Furthermore, analytical tools based on proteomics and lipidomics are being developed to facilitate investigations with high chemical sensitivity, specificity and spatial resolution to carry out the studies at the subcellular level.

Selected publications

  1. Laser Desorption Ionization Mass Spectrometry Imaging of Drosophila Brain Using Matrix Sublimation versus Modification with Nanoparticles, Nhu T. N. Phan, Amir Saeid Mohammadi, Masoumeh Dowlatshahi Pour and Andrew G. Ewing. Anal. Chem., 2016 Feb, 88 (3), pp 1734–1741
  2. An investigation on the mechanism of sublimed DHB matrix on molecular ion yields in SIMS imaging of brain tissue, Masoumeh Dowlatshahi Pour, Per Malmberg, Andrew G. Ewing, Anal Bioanal Chem., 2016 May, 408, pp 3071–3081
  3. Food induced changes of lipids in rat neuronal tissue visualized by ToF SIMS imaging, Masoumeh Dowlatshahi Pour, Eva Jennische, Stefan Lange, Andrew G. Ewing and Per Malmberg, Sci Rep., 2016 Sep, 6, pp 327971- 327979
  4. Zinc Regulates Chemical-Transmitter Storage in Nanometer Vesicles and Exocytosis Dynamics as Measured by Amperometry, Lin Ren, Masoumeh Dowlatshahi Pour, Soodabeh Majdi, Xianchan Li, Per Malmberg, and Andrew G. Ewing, Angew. Chem., Int. Ed. 2017, 56, pp 4970 –4975.